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Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

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Related Experiment Videos

Insights Into Stroke Risk and Prediction for Underweight Individuals.

Saeed Awad M Alqahtani1, Moutasem S Aboonq1

  • 1Professor of Human Physiology, Basic Medical Sciences Department, College of Medicine, Taibah University, Medina, Saudi Arabia.

Neurosciences (Riyadh, Saudi Arabia)
|June 4, 2026
PubMed
Summary
This summary is machine-generated.

Being underweight increases stroke risk and worsens outcomes, including higher mortality and poorer recovery. This highlights the need for better risk assessment and targeted interventions for underweight individuals.

Keywords:
PredictionRisk factorsStrokeUnderweight

Related Experiment Videos

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Obesity's link to stroke is well-established, but the risks of being underweight are often underestimated.
  • Underweight individuals experience significant negative consequences following a stroke.

Purpose of the Study:

  • To review the association between underweight status and stroke risk and outcomes.
  • To identify challenges in stroke prediction for underweight populations and suggest improvements.

Main Methods:

  • Systematic review of observational studies, case-control studies, and meta-analyses.
  • Analysis of existing stroke risk assessment tools and their limitations for underweight individuals.

Main Results:

  • Underweight individuals face increased mortality, impaired functional recovery, and higher rates of adverse cardiovascular events and recurrent strokes.
  • Current risk assessment tools, like the CHA2DS2-VASc score, are inadequate for predicting stroke risk in underweight populations.

Conclusions:

  • Underweight status poses a significant, overlooked risk for stroke and poor post-stroke outcomes.
  • There is a critical need for longitudinal studies and individualized risk assessments incorporating nutritional status to improve stroke prevention and management for underweight individuals.