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Cartap Hydrochloride Poisoning: Rarely Seen, Rarely Heard
Samata Chororia1, Satyabrata Guru1, Upendra Hansda1
1Department of Trauma and Emergency, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India.
Journal of Acute Medicine
|June 4, 2026
Summary
Cartap hydrochloride (CH) poisoning, though rare, can cause severe mixed acidosis. Early intervention with N-acetylcysteine (NAC) and non-invasive ventilation (NIV) is crucial for recovery.
Area of Science:
- Toxicology
- Emergency Medicine
- Pharmacology
Background:
- Cartap hydrochloride (CH) is a hazardous pesticide acting on nicotinic acetylcholine receptors.
- Severe CH poisoning can lead to respiratory failure and mixed acidosis.
- Human toxicity cases, especially with mixed acidosis, are infrequently reported.
Purpose of the Study:
- To report a rare case of severe Cartap hydrochloride poisoning.
- To highlight the clinical presentation and management of CH-induced mixed acidosis.
- To emphasize the efficacy of N-acetylcysteine and supportive care in CH toxicity.
Main Methods:
- A case report of a 25-year-old male with intentional Cartap hydrochloride ingestion.
- Clinical assessment including Glasgow Coma Scale (GCS) and heart rate (HR).
- Arterial blood gas (ABG) analysis to identify mixed acidosis.
- Treatment with non-invasive ventilation (NIV) and N-acetylcysteine (NAC).
Main Results:
- The patient presented with vomiting, drowsiness, and bradycardia.
- Initial ABG revealed mixed acidosis (pH 7.296).
- Treatment with NIV and NAC led to normalization of sensorium and ABG parameters within six hours.
Conclusions:
- Cartap hydrochloride poisoning requires prompt recognition and management.
- Mixed acidosis is a critical finding in severe CH toxicity.
- N-acetylcysteine and NIV are effective in treating Cartap hydrochloride poisoning and its complications.
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