What drives maternal RSV vaccine uptake? Understanding psychological predictors in Chilean women

Camila Salazar-Fernández1, María José Rivera-Baeza2, Natalia Salinas-Oñate1

  • 1Universidad de La Frontera, Temuco, Chile.

Respiratory syncytial virus (RSV) vaccination during pregnancy protects infants, yet its psychosocial determinants remain understudied. Guided by the Theory of Planned Behavior, this cross-sectional study examined predictors of RSV vaccination intention in a convenience sample of 463 Chilean women of reproductive age recruited through social media. Structural equation modeling showed good fit and explained 64.7% of the variance of intention, controlling for age, number of children, perceived social status, children`s vaccination status, and conspiracy beliefs. Positive attitudes were the strongest predictor (B = 0.422, p < 0.05), followed by negative attitudes (B = -0.284, p < 0.05), perceived infant risk (B = 0.155, p < 0.05), and pro-vaccination social norms (B = 0.100, p < 0.05). Perceived maternal risk was not significant (B = 0.027, p = 0.589). Findings highlight the role of attitudes and infant risk perceptions in shaping intention, with implications for communication strategies promoting maternal RSV vaccination.

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