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Updated: Jun 5, 2026
Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management
Published on: September 2, 2015
Permeable Liquid Metal-Based Fibrous Patch with Dual-Bond Interconnects for Reliable Sensing and Closed-Loop Wound
Shenxing Tan1, Yang Jiang2, Jinwei Cao3,4
1State Key Laboratory of Flexible Electronics (LOFE) & Institute of Flexible Electronics (IFE), Northwestern Polytechnical University, Shaanxi Key Laboratory of Flexible Electronics, Northwestern Polytechnical University, and MIIT Key Laboratory of Flexible Electronics (KLoFE), Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
This study introduces a novel liquid metal-based fibrous patch for wound care. This intelligent dressing offers real-time monitoring and on-demand antibacterial therapy, improving healing and infection control.
Area of Science:
- Biomaterials Science
- Wound Healing Technologies
- Medical Device Innovation
Background:
- Conventional wound dressings lack real-time monitoring and adaptive therapeutic capabilities.
- Effective infected wound management requires biocompatible, breathable materials with integrated sensing and treatment.
Purpose of the Study:
- To develop a permeable liquid metal-based fibrous patch (LMFP) for intelligent wound management.
- To integrate closed-loop temperature-humidity monitoring with on-demand photothermal antibacterial therapy.
Main Methods:
- Fabrication of a liquid metal (LM)-based fibrous patch (LMFP) using graphene oxide (GO) for stable LM-sensor coupling.
- Development of mechanoelectrical dual-bond interconnects for precise sensing in dynamic wound environments.
- In vitro and in vivo evaluations of the LMFP for wound monitoring, healing, and antibacterial therapy.
Main Results:
- The LMFP demonstrated precise temperature-humidity sensing capabilities in humid, dynamic conditions.
- The patch facilitated accelerated wound healing and effective infection control through on-demand photothermal therapy.
- Successful validation of intelligent closed-loop wound management was achieved.
Conclusions:
- The developed LMFP represents a next-generation intelligent wound dressing.
- It offers a breathable architecture, adaptive sensing, and responsive therapy for enhanced wound care.
- The patch shows significant potential for improved infection control and tissue regeneration in vulnerable skin.
