Expert consensus on robotic radiosurgery system for hepatocellular carcinoma

Area of Science:

• Oncology
• Radiotherapy
• Medical Physics

Background:

• Stereotactic ablative radiotherapy (SABR) is a growing treatment modality for hepatocellular carcinoma (HCC).
• The CyberKnife (CK) system represents an advanced robotic radiosurgery platform for delivering SABR.
• Accurate radiation delivery is critical in HCC treatment to spare surrounding healthy liver tissue.

Purpose of the Study:

• To establish a Chinese expert consensus on the application of the CyberKnife (CK) system for hepatocellular carcinoma (HCC) treatment.
• To outline the technical advantages of CK for delivering SABR in HCC.
• To provide guidance on the optimal use of CK in HCC management.

Main Methods:

• The study involved discussions among Chinese experts in oncology and radiation oncology.
• Consensus was reached on the principles and techniques for using the CyberKnife (CK) system in HCC.
• Key features of CK, including 3D multi-angle irradiation and respiratory tracking, were reviewed.

Main Results:

• The CyberKnife (CK) system enables precise patient positioning, treatment planning, and irradiation for HCC.
• CK's technology, including unique fiducial markers and respiratory tracking, effectively minimizes radiation to off-target areas due to respiratory motion.
• Favorable dose conformation and rapid dose fall-off in surrounding normal tissues are achieved with CK.

Conclusions:

• The CyberKnife (CK) system is a highly effective and accurate tool for delivering stereotactic ablative radiotherapy (SABR) in hepatocellular carcinoma (HCC) treatment.
• The established Chinese expert consensus provides a framework for the standardized and optimal utilization of CK for HCC.
• CK's advanced features contribute to improved treatment precision and potentially better clinical outcomes in HCC management.