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Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

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Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
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Updated: Jun 6, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Movement Disorders Associated With Breast Cancer: A Systematic Review.

Ravindra K Garg1, Amita Jain2, Akshay A Agrawal3

  • 1Department of Neurology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, Uttar Pradesh, India.

Annals of Indian Academy of Neurology
|June 4, 2026
PubMed
Summary
This summary is machine-generated.

Breast cancer-associated movement disorders are often immune-mediated and can precede cancer diagnosis. Early recognition and targeted evaluation are crucial for managing these neurological conditions.

Keywords:
Breast cancercerebellar ataxiamovement disordersonconeural antibodiesparaneoplastic neurological syndromes

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Last Updated: Jun 6, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Neurology
  • Oncology
  • Immunology

Background:

  • Movement disorders in breast cancer patients are diverse, stemming from paraneoplastic or treatment-related causes.
  • Understanding these neurological entities is critical for patient management.

Purpose of the Study:

  • To systematically review and characterize breast cancer-associated movement disorders.
  • Focus on clinical phenotypes, temporal links to cancer, immunological markers, treatments, and outcomes.

Main Methods:

  • Systematic review adhering to PRISMA 2020 guidelines.
  • Searched PubMed, Embase, Scopus, and Google Scholar for relevant case reports, series, and cohort studies.
  • Descriptive synthesis of extracted data.

Main Results:

  • 172 cases reviewed; cerebellar syndromes (47.7%) often preceded diagnosis, linked to anti-Yo antibodies, with poor outcomes.
  • Stiff-person syndrome (19.8%) associated with anti-amphiphysin antibodies showed better prognosis.
  • Other disorders included Parkinsonism, opsoclonus-myoclonus syndrome, with varied immune and treatment links.

Conclusions:

  • Breast cancer-associated movement disorders are primarily immune-mediated.
  • Phenotype-specific antibodies and distinct prognostic patterns necessitate early detection.
  • Targeted evaluation is vital for effective management.