Related Experiment Video
Updated: Jun 6, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
[Electrotherapy and sensory re-education as a treatment for chemotherapy-induced neuropathy]
Darlene Citlalli Pérez-Gómez1, María Fernanda Toro-Sashida1, Alejandro González-Ojeda2
1Instituto Mexicano Del Seguro Social, Centro Médico Nacional De Occidente, Hospital De Especialidades "Lic. Ignacio García Téllez", Servicio De Medicina De Rehabilitación. Guadalajara, Jalisco, México.
Background:
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is the main complication in cancer survivors, causing pain and other sensory alterations. Electrotherapy with Transcutaneous Electrical Nerve Stimulation (TENS) is a non-pharmacological resource for pain management, which consists of superficial application of alternate electrical current with cutaneous electrodes; being a safe, economical and portable alternative.
Objective:
to evaluate the effect of TENS on neuropathic pain and other sensory symptoms caused by CIPN secondary to platinum in patients with colon or rectal cancer.
Material And Methods:
a quasi-experimental study was conducted involving 10 rehabilitation sessions with TENS and sensory re-education to the patient group. Evaluations of neuropathic pain; superficial, deep and painful sensory alterations and single leg balance with eyes open and closed were performed before and after the intervention.
Results:
14 patients were recruited, all treated with platinum-based agents. Improvements were found in neuropathic pain (p < 0.001), sensory alterations (p < 0.001) and single leg balance with eyes open (p < 0.001) and closed (p < 0.05).
Conclusions:
rehabilitation with TENS and sensory re-education in patients with CIPN secondary to platinum-based agents significantly reduced neuropathic pain, sensory alterations (superficial, deep and painful) and improved single leg balance time with eyes open and closed.
More Related Videos
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Electroconvulsive Therapy
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Treatment Resistant Cancers
