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Updated: Jun 6, 2026

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
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Intraoperative flow cytometry as a potential alternative to fluorescence-guided surgery for glioma margin assessment

Eleni Romeo1, Spyridon Voulgaris1, George Markopoulos2

  • 1Department of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece; Neurosurgical Institute, University of Ioannina, Ioannina, Greece.

Clinical Neurology and Neurosurgery
|June 4, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
5-alaBrain tumorFlow cytometryGliomaIntraoperative

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...