Phase 1 trial of pre-operative image guided intensity modulated photon radiotherapy with simultaneously integrated
Kevin X Liu1, Yen-Lin Chen1, Beow Y Yeap2
1Department of Radiation Oncology, Mass General Brigham Cancer Institute, Harvard Medical School, Boston, MA, USA.
Abstract:
This phase 1 trial using intensity modulated photon pre-operative radiotherapy for patients with retroperitoneal sarcoma demonstrated that the dose can be safely escalated to 63.0 Gy to a select tumor volume deemed at high risk for positive margins. Thus, this approach is worthy of further prospective study with larger cohorts.


