Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioreactor Design and Operational System

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...

Health Information Technology and Healthcare Information System

Health Information Technology and Healthcare Information System

Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:

Operon Model

Operon Model

The operon model represents a fundamental mechanism of gene regulation in prokaryotes, enabling coordinated expression of genes involved in related metabolic or functional pathways. Operons consist of structural genes, a promoter, and an operator, with transcription regulated by repressors, activators, and small effector molecules.Structure and Function of OperonsAn operon is a cluster of structural genes transcribed together under the control of a single promoter. The promoter region...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Letter to the Editor Regarding "Integrating Thrombolysis into Routine Stroke Care in a Ghanaian Tertiary Hospital, Using the Implementation Research Logic Model (IRLM) as a Guiding Framework".

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026

Same author

Towards employee-centric HR: Understanding the link between opportunity-enhancing HR practices and employee taking charge at work.

Work (Reading, Mass.)·2026

Same author

Divergent Asymmetric Synthesis of Glutinosasins A-E.

Journal of the American Chemical Society·2026

Same author

The Impact of Digital Healthcare Adoption and Service Quality on Patient Satisfaction: The Moderating Role of Telehealth Services in Pakistan.

Journal of nursing management·2026

Same author

Asymmetric synthesis of 3,3-disubstituted oxindoles: methodologies and applications in natural product synthesis.

Natural product reports·2026

Same author

The role of ubiquitin system in ageing-related diseases and potential therapeutic opportunities.

Molecular biomedicine·2026

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

An Open-Source Normothermic Perfusion System Designed for Research Scientists

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

System design and data driven policy simulation for organ procurement networks using an OPO centre operations

Ziyue Wang¹, Mingxing Li¹, Zhiqiang Ma¹

¹School of Management, Jiangsu University, Zhenjiang, 212013, Jiangsu, People's Republic of China.

Scientific Reports

|June 4, 2026

Summary

Incentive redesign in organ procurement and transplantation can improve regional equity. This simulation framework helps test policies for better organ allocation and reduced disparities.

Keywords:

Behavioral operations research Decision-making Healthcare systems Organ procurement operations Simulation and modelling System design Transplant network governance

Related Experiment Videos

Last Updated: Jun 6, 2026

An Open-Source Normothermic Perfusion System Designed for Research Scientists

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

Area of Science:

Health Services Research
Operations Research
Public Policy

Background:

Healthcare organ procurement and transplantation networks operate as complex systems.
Existing governance and incentives contribute to persistent regional inequities in organ allocation.
Understanding organizational behavior is crucial for improving system performance.

Purpose of the Study:

To develop a data-driven, simulation-based framework for evaluating and redesigning incentive mechanisms.
To model transplant center responses under different governance regimes.
To assess the impact of equity-weighted incentives on system performance.

Main Methods:

Utilized SRTR-style center-level activity data.
Constructed a Java-based policy-simulation environment.
Formulated center utility based on transplant volumes, regional characteristics, and operating costs.
Assessed system performance using aggregate welfare and distributional equity metrics.

Main Results:

Simulation experiments revealed quantifiable equity-efficiency trade-offs.
Identified parameter regions where incentive redesign improves regional equity with minimal performance loss.
Demonstrated the impact of equity-weighted incentives on transplant center behavior.

Conclusions:

The developed framework offers a transparent tool for regulators to test policy reforms.
Integrating system design, behavioral modeling, and incentive analysis can optimize organ procurement networks.
Policy interventions can mitigate regional inequities in organ transplantation.