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Artificial Intelligence for Procedural Guidance of Spinal Epidural Steroid Injections: A Scoping Review
Aleya DeVries1, Taylor Yuska1, Suzanne I Riskin1
1Department of Foundational Sciences, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.
Cureus
|June 5, 2026
Summary
Artificial intelligence (AI) can improve spinal epidural steroid injections (SESI) by enhancing image interpretation and planning. While showing promise, further research is needed for widespread clinical adoption of AI in SESI procedures.
Area of Science:
- Medical Imaging and Interventional Radiology
- Artificial Intelligence in Medicine
- Spinal Interventions
Background:
- Spinal epidural steroid injections (SESI) are common for radiating pain but face challenges with precision and outcomes.
- Artificial intelligence (AI) is being explored to improve medical procedures, including SESI.
Purpose of the Study:
- To conduct a scoping review summarizing current evidence on AI's role in guiding SESI procedures.
- To identify AI applications in pre-procedural planning, intra-procedural guidance, and post-procedural outcome prediction for SESI.
Main Methods:
- Searched PubMed, Web of Science, and Embase for English-language primary studies from 2015-2025.
- Included nine studies utilizing AI architectures like machine learning and deep learning.
- Categorized evidence into pre-procedural planning, intra-procedural guidance, and outcome prediction.
Main Results:
- Most studies showed AI improved trajectory planning, needle localization, segmentation, and predictive performance.
- Potential benefits include reduced procedure time, lower radiation exposure, and better patient selection.
- Limitations include model dependency, small datasets, and underrepresentation of certain patient groups.
Conclusions:
- AI demonstrates significant potential to enhance the guidance and outcomes of SESI.
- Further large-scale, standardized research is necessary before routine clinical implementation.
- AI may optimize patient selection and procedural efficiency in SESI.
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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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