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Related Concept Videos

Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.
Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Propagation of Action Potentials01:23

Propagation of Action Potentials

The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Integration of Synaptic Events01:28

Integration of Synaptic Events

Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...

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Related Experiment Video

Updated: Jun 6, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

Three factor delay learning rules for spiking neural networks.

Luke Vassallo1, Nima Taherinejad1

  • 1ECLECTX Team, Institute of Computer Engineering, Heidelberg University, Heidelberg, Germany.

Frontiers in Neuroscience
|June 5, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces learnable delays to spiking neural networks (SNNs) for improved temporal pattern recognition. Online learning of weights and delays enhances accuracy and efficiency, benefiting resource-constrained neuromorphic processors.

Keywords:
neuromorphic computingonline learningspiking neural networks (SNNs)synaptic and axonal delaysthree-factor learning rules

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Last Updated: Jun 6, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
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Published on: March 25, 2014

Area of Science:

  • Computational Neuroscience
  • Machine Learning

Background:

  • Spiking neural networks (SNNs) process spatiotemporal data but often lack effective temporal pattern recognition due to limited learnable parameters.
  • Existing methods for incorporating delays require large networks and offline learning, hindering real-time applications.

Purpose of the Study:

  • To introduce learnable synaptic and axonal delays into leaky integrate and fire (LIF)-based SNNs.
  • To develop online three-factor learning rules for simultaneously learning weights and delays.
  • To enable efficient, real-time temporal pattern recognition in resource-constrained environments.

Main Methods:

  • Incorporated synaptic and axonal delays into feedforward and recurrent LIF SNNs.
  • Proposed novel three-factor learning rules for online weight and delay adaptation.
  • Utilized a smooth Gaussian surrogate for approximating spike derivatives in eligibility trace calculations.

Main Results:

  • Delay incorporation improved accuracy by up to 18% compared to weights-only SNNs.
  • Joint learning of weights and delays yielded up to 14% higher accuracy for comparable network sizes.
  • Achieved competitive accuracy on the SHD speech recognition dataset, comparable to offline methods.
  • Reduced model size by 6.6x and inference latency by 50% compared to state-of-the-art methods.

Conclusions:

  • Jointly learning weights and delays in SNNs significantly enhances temporal classification performance.
  • The proposed online learning method is suitable for power- and area-constrained neuromorphic processors.
  • This approach enables on-device learning and reduces memory requirements for SNNs.