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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
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Related Experiment Video

Updated: Jun 6, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
07:48

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

Biomedical implants and medical radiation.

S A Halim1, Rozy Kamal1,2

  • 1Department of Nuclear Medicine, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Biomedical Materials (Bristol, England)
|June 5, 2026
PubMed
Summary

Medical radiation exposure alters biomedical implant materials, impacting their performance and reliability. This review details radiation effects on common implant materials and suggests strategies for developing radiation-tolerant next-generation implants.

Keywords:
biomedical implantsionizing radiationmaterial interactionsradioprotective strategies

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Area of Science:

  • Biomaterials Science
  • Medical Physics
  • Radiology

Background:

  • Biomedical implants are increasingly used in conjunction with medical radiation procedures.
  • Ionizing radiation exposure can induce physicochemical changes in implant materials.
  • These changes affect mechanical properties, surface stability, and biocompatibility, influencing clinical outcomes.

Purpose of the Study:

  • To review the effects of ionizing radiation on commonly used biomedical implant materials.
  • To discuss degradation mechanisms, experimental findings, and clinical implications.
  • To explore strategies for developing radiation-tolerant implant materials.

Main Methods:

  • Literature review of studies on ionizing radiation effects on metals, ceramics, polymers, and composites used in implants.
  • Analysis of structural degradation mechanisms and experimental outcomes.
  • Synthesis of clinical implications and future research directions.

Main Results:

  • Ionizing radiation causes structural degradation in various implant materials, affecting their performance.
  • Specific effects vary depending on the material type (metals, ceramics, polymers, composites).
  • Clinical reliability and tissue integration of implants are compromised by radiation-induced modifications.

Conclusions:

  • There is a critical need to understand and mitigate the impact of medical radiation on biomedical implants.
  • Development of radiation-tolerant materials and standardized testing is essential.
  • Informed material selection and design optimization are crucial for next-generation implants in radiation-rich environments.