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Related Experiment Video

Updated: Jun 6, 2026

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

Association Between Hair Lithium Levels and Suicide: A Case-Control Study.

Orquídia Neves, Vasco Mendes Águia, Rui Azevedo

Archives of Suicide Research : Official Journal of the International Academy for Suicide Research

|June 5, 2026

Summary

This summary is machine-generated.

This study found no significant difference in hair lithium levels between suicide victims and controls. Mental disorders, however, remained a strong predictor of suicide in the studied population.

Keywords:

Association case-control lithium scalp hair suicide

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The Tail Suspension Test

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Last Updated: Jun 6, 2026

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The Tail Suspension Test

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Published on: January 28, 2012

Area of Science:

Forensic Science
Toxicology
Psychiatry

Background:

Hair analysis offers a stable method for long-term trace element monitoring, reflecting chronic exposure.
Previous research suggests links between low hair lithium (Li) levels and mental illness or violent behavior.
The relationship between hair Li levels and suicide has not been previously investigated.

Purpose of the Study:

To investigate the association between hair lithium concentrations and suicide.
To determine if hair Li levels can serve as a biomarker for suicide risk.

Main Methods:

A case-control study was conducted on deceased individuals.
Hair samples from 25 suicide cases and 27 non-suicide controls were analyzed.
Lithium concentration was measured using Inductively Coupled Plasma-Mass Spectrometry.

Main Results:

No significant differences in hair Li content were observed between the suicide and control groups.
Hair Li concentrations ranged from <3 to 42 µg/kg, with low variability.
Mental disorder was significantly associated with suicide (OR, 22.74; p=0.009) after adjustment for other factors.

Conclusions:

Hair lithium concentrations do not differ between suicide victims and controls in this population.
No association was found between hair Li levels and suicide in this study.
Mental disorder is a significant risk factor for suicide.