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Disguised discoloration: Minocycline-induced pigmented cardiac valves
Natasha L Salmen1, Taylor M Pong2, Sabrina Bennett2
1College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
None:
Tetracyclines are used for a variety of dermatologic conditions, and a known side effect of this therapy is hyperpigmentation in multiple tissues throughout the body. We present the case of a 66-year-old man who underwent aortic valve replacement and was found to have discoloration of the aortic valve leaflets associated with his chronic use of minocycline for rosacea. Minocycline-induced pigmentation of cardiac valves is a documented, although uncommon, phenomenon. There is no evidence linking valve pigmentation to functional valve defects. This case highlights an infrequent manifestation of minocycline-induced pigmentation.
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