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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

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Related Experiment Video

Updated: Jun 6, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Blue nevus-like melanoma: A rare entity.

Lanyu Sun1, Mafalda Pinho2, Catarina Quadros2

  • 1Serviço de Dermatovenereologia, Hospital de Santa Maria, Unidade Local de Saúde Santa Maria, Lisboa, Portugal.

Dermatology Online Journal
|June 5, 2026
PubMed
Summary

Blue nevus-like melanoma (BNM) is a rare and aggressive skin cancer variant. This case highlights its rapid progression and widespread metastasis despite immunotherapy, emphasizing the need for new treatments.

Area of Science:

  • Oncology
  • Dermatopathology

Background:

  • Blue nevus-like melanoma (BNM) is a rare variant of melanoma.
  • It often arises from pre-existing blue nevi and exhibits aggressive behavior.
Keywords:
blue-nevus melanomaimmunotherapymetastasis

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