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Blue nevus-like melanoma: A rare entity.
Lanyu Sun1, Mafalda Pinho2, Catarina Quadros2
1Serviço de Dermatovenereologia, Hospital de Santa Maria, Unidade Local de Saúde Santa Maria, Lisboa, Portugal.
Dermatology Online Journal
|June 5, 2026
Summary
Blue nevus-like melanoma (BNM) is a rare and aggressive skin cancer variant. This case highlights its rapid progression and widespread metastasis despite immunotherapy, emphasizing the need for new treatments.
Area of Science:
- Oncology
- Dermatopathology
Background:
- Blue nevus-like melanoma (BNM) is a rare variant of melanoma.
- It often arises from pre-existing blue nevi and exhibits aggressive behavior.
Related Concept Videos
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:19Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
01:14Changes in Skin Color: Clinical Perspectives
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Albinism
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Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...