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Updated: Jun 6, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
Patchy presentation of central centrifugal cicatricial alopecia
Ruhi Nayak1, Alvaro C Laga2, Alicia L Kenyon2
1Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Abstract:
Central centrifugal cicatricial alopecia (CCCA) is a form of scarring alopecia typically characterized by progressive hair loss that begins at the crown or vertex of the scalp and expands circumferentially over time. Although most commonly described and diagnosed in women of African descent, CCCA can also occur in men. We describe the case of a 38-year-old man of African descent with a patchy presentation of CCCA. Unlike the classic distribution reported in the literature, this patient exhibited multifocal patchy areas of scarring hair loss. This case highlights the importance of considering CCCA in younger men presenting with atypical alopecia patterns to ensure accurate diagnosis and appropriate management.
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