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Related Experiment Video

Updated: Jun 6, 2026

TiO2-coated Hollow Glass Microspheres with Superhydrophobic and High IR-reflective Properties Synthesized by a Soft-chemistry Method
07:37

TiO2-coated Hollow Glass Microspheres with Superhydrophobic and High IR-reflective Properties Synthesized by a Soft-chemistry Method

Published on: April 26, 2017

Encapsulating TiO2 Nanoparticles in Chitosan-Based Porous Microspheres as Multifunctional UV Filters.

Yunxing Li1, Xue Cai1, Beizhe Chang1

  • 1Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.

Langmuir : the ACS Journal of Surfaces and Colloids
|June 5, 2026
PubMed
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Researchers developed safer titanium dioxide nanoparticles (TiO2 NPs) using a Pickering double emulsion method. Encapsulating TiO2 NPs in chitosan microspheres reduced toxicity and enhanced UV protection in sunscreens.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Titanium dioxide nanoparticles (TiO2 NPs) are common UV filters but pose safety concerns due to photocatalytic activity and phototoxicity.
  • Developing safer, effective UV filtering materials is crucial for consumer products and health.

Purpose of the Study:

  • To create a novel encapsulation strategy for TiO2 NPs to mitigate their phototoxicity.
  • To develop multifunctional chitosan-based porous microspheres (TiO2@CS-PMs) for enhanced UV protection and biocompatibility.

Main Methods:

  • Utilized a Pickering double emulsion templating strategy to synthesize chitosan-based porous microspheres encapsulating TiO2 NPs.
  • Investigated the microstructure, mass loading, UV attenuation, and phototoxicity of the fabricated TiO2@CS-PMs.

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A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Related Experiment Videos

Last Updated: Jun 6, 2026

TiO2-coated Hollow Glass Microspheres with Superhydrophobic and High IR-reflective Properties Synthesized by a Soft-chemistry Method
07:37

TiO2-coated Hollow Glass Microspheres with Superhydrophobic and High IR-reflective Properties Synthesized by a Soft-chemistry Method

Published on: April 26, 2017

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

  • Assessed the performance of TiO2@CS-PMs in a sunscreen formulation for sun protection factor (SPF) and cellular photoprotection.

    • Main Results:

    • The encapsulation strategy effectively confined TiO2 NPs within a chitosan matrix, reducing UV-induced reactive oxygen species generation.
    • TiO2@CS-PMs demonstrated significantly lower phototoxicity to HaCaT cells compared to bare TiO2 NPs.
    • The microspheres enhanced UV attenuation and provided higher SPF and cellular photoprotection at lower NP concentrations.
    • Chitosan matrix imparted antibacterial activity to the formulation.

    Conclusions:

    • Pickering double emulsion templating offers a versatile platform for managing nanoparticle photochemistry and developing safer UV filters.
    • TiO2@CS-PMs represent a promising advancement in creating safer, multifunctional UV-blocking agents with improved efficacy and biocompatibility.