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Updated: Jun 6, 2026
06:39
Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Postpartum depression: challenges in diagnosis and destigmatization]
S A Kashchenko1, A A Arutyunyan2, S R Shakhnidaryan2
1Pirogov Russian National Research Medical University, Moscow, Russia.
Summary
Postpartum depression (PPD) affects 17% of women globally. Addressing stigma and using interdisciplinary approaches are key to overcoming diagnostic barriers and improving maternal and infant health outcomes.
Area of Science:
- Reproductive Health
- Mental Health
- Public Health
Background:
- Postpartum depression (PPD) is a prevalent mental disorder affecting 17% of women worldwide.
- PPD negatively impacts maternal psychophysiological health and infant development.
- A significant gap exists between PPD diagnostic methods and care coverage, exacerbated by stigma.
Purpose of the Study:
- To review recent international findings on obstacles to diagnosing PPD.
- To evaluate strategies for overcoming diagnostic challenges.
- To emphasize the importance of addressing stigma in PPD care.
Main Methods:
- Systematic literature review of international scientific findings.
- Searched databases: PubMed, Scopus, ScienceDirect, Web of Science.
- Included publications from 2016 to 2025.
Main Results:
- Stigma is a primary barrier, causing women to conceal symptoms and avoid seeking help.
- Multi-level barriers hinder the diagnosis and treatment of PPD.
- Effective strategies involve interdisciplinary approaches in destigmatized environments.
Conclusions:
- Addressing stigma is crucial for improving maternal and infant health.
- Early detection, risk assessment, and timely intervention enhance PPD outcomes.
- An interdisciplinary, destigmatized approach facilitates better care for affected mothers.
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