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Updated: Jun 6, 2026

Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety
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Published on: September 15, 2023

Guidelines for Reporting New Monoclonal Antibodies: Improving Transparency, Reproducibility, and Research Utility

Andrei Moroz1, Cory L Brooks2

  • 1Department of Clinical Analysis, Monoclonal Antibody Laboratory, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
|June 5, 2026
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...