Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra-flexible optoelectronic stimulator converts tissue-attenuated weak light into electrical signals for cardiac remodeling.

Nature communications·2026
Same author

Facile synthesis of carboxymethyl chitosan quaternary ammonium derivatives and the evaluation on antioxidant potential in vitro and in vivo.

Food chemistry·2026
Same author

Cross-Regional Transfer Learning for Interpretable Prediction of Groundwater Uranium Contamination.

Environmental science & technology·2026
Same author

Phosphatidylserine-everted erythrocyte membrane vesicles enhance efferocytosis and remodeling of vascular grafts.

Nature communications·2026
Same author

Adjuvant chemotherapy for completely resected stage IB-IIA non-small cell lung cancer according to the AJCC 8th edition staging system: a real-world retrospective cohort study based on the SEER database.

Translational lung cancer research·2026
Same author

Unveiling glycaemic variability patterns linked to the triglyceride-glucose index in type 2 diabetes: Insights from continuous glucose monitoring.

Diabetes, obesity & metabolism·2026

Related Experiment Video

Updated: Jun 6, 2026

In Vivo Three-Dimensional Two-Photon Microscopy to Study Conducted Vascular Responses by Local ATP Ejection Using a Glass Micro-Pipette
10:54

In Vivo Three-Dimensional Two-Photon Microscopy to Study Conducted Vascular Responses by Local ATP Ejection Using a Glass Micro-Pipette

Published on: June 7, 2019

Photothermal Ablation Blotting for Capillary-Scale Microvasculature Engineering.

Kexin Feng1, Shuaibing Liu1, Ruiyue Zhao1

  • 1Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, China.

Advanced Materials (Deerfield Beach, Fla.)
|June 5, 2026
PubMed
Summary

This study introduces a photothermal ablation blotting (PAB) method to engineer perfusable microvascular networks in hydrogels. The technique creates robust, hierarchical vascular channels, improving tissue integration for regenerative medicine applications.

Keywords:
microvasculature engineeringperfusable infiltrationphotothermal ablation blottingphotothermal fibersrevascularization

More Related Videos

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks
10:53

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Published on: January 3, 2017

Capillary Force Lithography for Cardiac Tissue Engineering
10:09

Capillary Force Lithography for Cardiac Tissue Engineering

Published on: June 10, 2014

Related Experiment Videos

Last Updated: Jun 6, 2026

In Vivo Three-Dimensional Two-Photon Microscopy to Study Conducted Vascular Responses by Local ATP Ejection Using a Glass Micro-Pipette
10:54

In Vivo Three-Dimensional Two-Photon Microscopy to Study Conducted Vascular Responses by Local ATP Ejection Using a Glass Micro-Pipette

Published on: June 7, 2019

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks
10:53

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Published on: January 3, 2017

Capillary Force Lithography for Cardiac Tissue Engineering
10:09

Capillary Force Lithography for Cardiac Tissue Engineering

Published on: June 10, 2014

Area of Science:

  • Biomaterials Engineering
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Integrating engineered tissues with host vasculature, especially at the capillary level, is a major challenge.
  • Developing methods for creating functional microvascular networks is crucial for graft success.

Purpose of the Study:

  • To develop a novel strategy for engineering perfusable, robust, and hierarchically branched microvascular networks within hydrogel matrices.
  • To demonstrate the efficacy of this method in supporting vascular integration and tissue remodeling in vivo.

Main Methods:

  • Utilized a photothermal ablation blotting (PAB) strategy employing bioresorbable photothermal fibers (PTF) as a sculpting template.
  • Engineered microchannels of multiple diameters using sequential near-infrared (NIR) and UV activation.
  • Enhanced hydrogel mechanical properties through fiber reinforcement, creating photothermal microchannel hydrogels (PMH).

Main Results:

  • The PMH platform demonstrated efficient in vitro perfusion and cellular infiltration.
  • In vivo studies using rat subcutaneous and myocardial infarction (MI) models showed successful vascular integration and tissue remodeling.
  • The PAB method proved scalable and adaptable for capillary-scale microvasculature engineering.

Conclusions:

  • The PAB strategy offers a promising solution for creating functional microvascular networks in engineered tissues.
  • This technique has broad applicability in regenerative medicine and soft tissue reconstruction, addressing critical integration bottlenecks.