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Bridge nodes linking neuroticism to depressive symptoms: An item-level network and intervention simulation study
Chenfan Yang1, Nurul Fazzuan Khalid2
1School of Educational Studies, Universiti Sains Malaysia, Penang, 11800, Malaysia; Guangdong Business and Technology University, Zhaoqing, 526000, China.
Acta Psychologica
|June 5, 2026
Summary
Neuroticism and depression in college students are linked through specific traits like feeling fed up, low self-esteem, loneliness, and depressed mood. Targeting these key factors could significantly reduce depression symptoms.
Area of Science:
- Psychology
- Mental Health
- Network Analysis
Background:
- Depression is a prevalent mental health issue in college students.
- Neuroticism is a significant personality risk factor for depression.
- Limited research exists on item-level interactions between neuroticism and depression.
Purpose of the Study:
- To investigate the item-level network structure connecting neuroticism and depressive symptoms in Chinese college students.
- To identify key bridge nodes representing the interplay between neurotic traits and depressive symptoms.
- To evaluate the potential impact of interventions targeting these bridge nodes.
Main Methods:
- Recruited 4421 Chinese college students.
- Assessed neurotic traits and depressive symptoms using standardized instruments.
- Employed a mixed graphical model (MGM) to construct a network and identify bridge nodes.
- Conducted simulation-based intervention analysis using the CrossCut metric.
Main Results:
- Identified four key bridge nodes: N5 (Fed up), D2 (Depressed mood), D6 (Low self-esteem), and N11 (Loneliness).
- Simulated interventions targeting individual nodes reduced CrossCut by 16-23%.
- Jointly targeting all four bridge nodes resulted in a 65.9% reduction in CrossCut.
Conclusions:
- Emotional reactivity, self-critical cognition, and interpersonal disconnection are crucial links between neuroticism and depression.
- These identified bridge features are potential targets for clinical interventions.
- Interventions focused on these specific traits may effectively reduce the association between neuroticism and depressive symptoms.
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