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Multifocal jejunal histiocytic sarcoma presenting with dual intussusception
Bolin He1, Min Liu2, Shu-Bang Cheng2
1Department of Gastrointestinal Surgery, The People's Hospital of Longhua Shenzhen, Shenzhen, China hebolin921115@163.com.
BMJ Case Reports
|June 5, 2026
Summary
Histiocytic sarcoma (HS) of the small intestine is rare. This case highlights multifocal HS causing jejunal intussusception in an adult, emphasizing thorough diagnosis for rare neoplasms.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Histiocytic sarcoma (HS) is a rare malignant neoplasm.
- Small intestinal HS is exceptionally uncommon, posing diagnostic challenges.
Purpose of the Study:
- To report a rare case of multifocal histiocytic sarcoma of the small intestine causing jejunal intussusception.
- To emphasize the importance of considering rare neoplasms in adult intussusception.
Main Methods:
- Case report of a patient presenting with acute abdominal pain.
- Diagnostic workup included emergency laparoscopy, open resection, histopathology, and immunohistochemistry.
- Identification and resection of multiple jejunal tumors.
Main Results:
- Multifocal histiocytic sarcoma of the jejunum was confirmed.
- Two synchronous jejunal intussusceptions were caused by HS lesions.
- Mesenteric nodal metastasis was present; 13 tumors were identified.
Conclusions:
- Adult intussusception can be caused by rare neoplasms like HS.
- Thorough intraoperative exploration and extensive histopathology are crucial for diagnosis.
- Early consideration of rare tumors is vital for appropriate patient management.
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