Enhanced Outcomes of Intravascular Ultrasound-Guided Versus Angiography-Guided Percutaneous Coronary Intervention in
Zhengya Fang1, Suwen Zhu1, Shaodong Zhang1
1Department of Cardiovascular Medicine, Liyang People's Hospital, Liyang, Jiangsu, China.
Insights
Intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in coronary heart disease (CHD) patients improved stent implantation and reduced major adverse cardiovascular events (MACE). IVUS guidance offers superior outcomes compared to traditional coronary angiography (CAG) guidance alone.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Coronary heart disease (CHD) remains a leading cause of mortality worldwide.
- Percutaneous coronary intervention (PCI) is a common treatment for CHD.
- Optimizing PCI outcomes is crucial for patient prognosis.
Purpose of the Study:
- To compare the clinical efficacy of intravascular ultrasound (IVUS)-guided PCI versus coronary angiography (CAG)-guided PCI in CHD patients.
- To evaluate the impact of IVUS guidance on lesion characteristics, stent parameters, and clinical outcomes.
Main Methods:
- A randomized controlled trial involving 100 CHD patients.
- Patients were assigned to either CAG-guided PCI (control group) or IVUS-guided PCI (study group).
- Outcomes assessed included lesion characteristics, stent parameters, complications, MACE, and restenosis over a one-year follow-up.
Main Results:
- IVUS-guided PCI resulted in a wider minimal lumen diameter and reduced diameter stenosis and plaque burden post-stenting.
- Key stent implantation parameters, including minimum stent cross-sectional area, were significantly improved with IVUS guidance.
- The study group showed a lower incidence of MACE during one-year follow-up compared to the control group.
Conclusions:
- IVUS-guided PCI is more effective than CAG-guided PCI in improving coronary blood flow and stent implantation in CHD patients.
- IVUS guidance significantly reduces the incidence of major adverse cardiovascular events.
- This technique enhances the safety and efficacy of percutaneous coronary intervention for coronary heart disease.
Abstract:
ObjectiveThis study aimed to compare the clinical efficacy of intravascular ultrasound (IVUS)-guided versus coronary angiography (CAG)-guided percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD).MethodsOne hundred CHD patients were randomized into two groups. The control group (n = 50) underwent CAG-guided PCI, while the study group (n = 50) underwent IVUS examination following CAG and received IVUS-guided PCI. Evaluated outcomes included lesion characteristics, stent parameters, postoperative complications, major adverse cardiovascular events (MACE), and coronary restenosis.ResultsFollowing stent implantation, the minimal lumen diameter in the study group was wider than that in the control group, while the diameter stenosis and plaque burden were lower than those in the control group (P < .05). The maximum stent diameter, maximum balloon diameter for post-dilation, maximum balloon pressure, immediate postoperative minimum stent diameter, and minimum stent cross-sectional area in the study group were greater than those in the control group. Additionally, the stent placement success rate in the study group was higher than that in the control group (P < .05). There was no difference in postoperative complications between the two groups (P > .05). During one-year follow-up, the study group had lower incidence of MACE compared with the control group (P < .05). The incidence of stent restenosis in the study group was lower than that in the control group, but the difference was not statistically significant (P > .05).ConclusionCompared with CAG guidance alone, IVUS-guided PCI for CHD can effectively improve coronary blood flow, enhance stent implantation efficacy, and reduce MACE incidence.
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