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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Mutational Landscape and Clinical Outcomes in AML With Sole Trisomy 8

Ehsan Bahrami Hezaveh1,2, Mark Anthony Turingan1,2, Qianghua Zhou1,2

  • 1Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

Hematological Oncology
|June 6, 2026
PubMed
Summary

Acute myeloid leukemia with sole chromosome 8 gain (sole +8 AML) is rare. High rates of myelodysplasia-related gene mutations in sole +8 AML patients correlate with inferior survival, highlighting their prognostic significance.

Keywords:
AMLisolated trisomy 8mutationsprognosis

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