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Deep learning reconstruction improves appendix visualization on pediatric magnetic resonance imaging (MRI): a
Sebastian Gallo-Bernal1,2, Valeria Pena-Trujillo3,4, Navaira Shoaib3,5
1Massachusetts General Hospital/Mass General Brigham, Boston, MA, USA. sgallobernal@mgh.harvard.edu.
Pediatric Radiology
|June 6, 2026
Summary
Deep learning reconstruction (DLR) with thin-slice MRI improves appendix visualization and image quality in pediatric appendicitis evaluations. This technique enhances diagnostic capabilities for children suspected of having appendicitis.
Area of Science:
- Radiology and Medical Imaging
- Artificial Intelligence in Medicine
- Pediatric Healthcare
Background:
- Thin-slice MRI offers potential for better appendix visualization in pediatric appendicitis.
- However, reduced slice thickness typically lowers signal-to-noise ratio (SNR) and degrades image quality.
- Deep learning reconstruction (DLR) can denoise thin-slice images, potentially overcoming these limitations.
Purpose of the Study:
- To assess if 2-mm T2-weighted MRI with DLR enhances appendix visualization and diagnostic performance compared to standard 4-mm MRI in pediatric appendicitis.
- To evaluate the impact of DLR on image quality and diagnostic confidence.
Main Methods:
- Prospective study of 82 pediatric patients with suspected appendicitis.
- Comparison of standard 4-mm MRI with thin-slice 2-mm MRI enhanced by DLR (2-mm+DLR).
- Radiologist assessment of appendix visualization, diagnostic confidence, image quality, and ancillary findings; objective SNR measurements.
Main Results:
- 2-mm+DLR images showed comparable SNR to standard 4-mm images.
- Improved appendix visualization with 2-mm+DLR (88.2%) versus 4-mm MRI (83.3%).
- Higher overall diagnostic image quality with 2-mm+DLR (median 5 vs 4), with similar diagnostic confidence.
Conclusions:
- DLR-enhanced 2-mm MRI improves appendix visualization and image quality in pediatric appendicitis.
- The technique does not reduce reader confidence or specificity.
- Thin-slice DLR MRI aids in depicting the appendix and other abdominal pathologies in children.
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