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The relationship between cognitive dysfunction and suicide crisis syndrome symptoms
Tyler Ulch1, Anna Stefania Prekas2, Amanda R Edwards1
1Teachers College, Columbia University, 525 W 120th St, New York, NY, 10027, United States.
Journal of Affective Disorders
|June 6, 2026
Summary
Suicide Crisis Syndrome (SCS) symptoms, especially affective disturbance, are linked to executive function deficits. This impairment may decrease over time with treatment, suggesting SCS is state-dependent.
Area of Science:
- Psychiatry
- Neuroscience
- Clinical Psychology
Background:
- Suicide Crisis Syndrome (SCS) is a proposed diagnostic construct for the DSM.
- DSM inclusion requires evidence of functional impairment.
- This study investigates the link between SCS and executive function (EF).
Purpose of the Study:
- To test the hypothesis that SCS is associated with deficits in executive function (EF).
- To examine the relationship between SCS symptoms and EF in psychiatric inpatients.
Main Methods:
- Eighty-five inpatients assessed at intake and 64 at discharge.
- SCS symptoms measured using the 15-item SCS checklist (SCS-C).
- EF assessed via Trail Making Test, Stroop Test, and Digits tasks; analyzed with correlations, ANOVA, and GLM.
Main Results:
- SCS-C scores decreased from intake to discharge.
- A negative association between SCS Affective Disturbance and EF at intake attenuated by discharge.
- GLM revealed a significant time-by-association interaction, controlling for age.
Conclusions:
- SCS symptoms, particularly affective disturbance, may be linked to executive dysfunction.
- This executive dysfunction may compromise judgment and increase impulsivity.
- The findings suggest SCS is associated with state-dependent cognitive impairment.
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