Related Experiment Video
Updated: Jun 8, 2026
Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Effect of implementing an evidence-based clinical practice intra-hospital transport guideline for hospitalized
Yang Li1, Yuxia Yang1, Jing Hu2
1Pediatric Intensive Care Unit, Children's Hospital of Fudan University, Shanghai, China.
Insights
Implementing a new guideline for intra-hospital transfers (IHT) in children improved healthcare provider knowledge and reduced adverse events. Further refinement is needed to increase patient participation and optimize transport time.
Area of Science:
- Pediatric Healthcare Quality Improvement
- Clinical Practice Guideline Implementation
- Patient Safety in Hospitals
Background:
- Intra-hospital transfers (IHT) are common in pediatric care, particularly for emergency and postoperative patients.
- Standardizing IHT processes is crucial for minimizing adverse events and improving outcomes in hospitalized children.
- An evidence-based clinical practice guideline for pediatric IHT was developed to address these needs.
Purpose of the Study:
- To evaluate the implementation process of an evidence-based clinical practice guideline for intra-hospital transfers (IHT) in hospitalized children.
- To assess the guideline's effectiveness on patient outcomes, healthcare professionals' knowledge and behavior, and the hospital's organizational context.
- To utilize the RE-AIM framework for a comprehensive evaluation of the implementation.
Main Methods:
- A Type III hybrid effectiveness-implementation design was employed, featuring a pre-post intervention trial.
- Data collected included patient demographics, transport-related outcomes, and healthcare provider knowledge and compliance.
- The RE-AIM framework assessed Reach, Effectiveness, Adoption, and Implementation across 213 IHTs involving 110 healthcare professionals.
Main Results:
- Patient participation (Reach) was suboptimal at 33%.
- The guideline significantly improved healthcare professionals' knowledge (median 40 to 76, p<0.001), reduced adverse events (12 vs 4, p=0.047), and decreased handover time (5 to 4 min, p<0.001).
- Handover information completeness improved significantly (median score 5 to 20, p<0.001), though total transport time increased (14 to 19 min, p<0.05).
Conclusions:
- The RE-AIM-based evaluation confirmed the guideline's effectiveness in enhancing healthcare professional knowledge and compliance, reducing adverse events, and optimizing handover efficiency.
- Despite positive clinical outcomes, limited patient participation and increased transport duration indicate areas for further improvement.
- The study highlights the importance of a structured approach to guideline implementation for improving pediatric intra-hospital transfer safety.
Background:
Intra-hospital transfers (IHT) of hospitalized children are unavoidable practices often performed with emergency patients and postoperative patients. Standardizing IHT processes to minimize adverse events might improve children's outcomes. We developed an evidence-based clinical practice IHT guideline for hospitalized children. The aim of this study was to evaluate the implementation process and the effectiveness of the implementation of this guideline on patient outcomes, healthcare professionals' knowledge and behavior, and hospital organizational context.
Methods:
A type III hybrid effectiveness-implementation design was adopted, using a pre-post intervention trial (January-December 2024). Data of patient demographics, transport-related outcomes, and healthcare providers' knowledge and compliance were collected. We used the RE-AIM framework to assess effectiveness across four dimensions: Reach, Effectiveness, Adoption, and Implementation. Totally, 110 healthcare professionals conducted 213 IHTs of eligible children (109 children in the pre-intervention group and 104 in post-intervention group).
Results:
The Reach outcomes demonstrated that participation among hospitalized children (n = 312) was suboptimal at 33% (104/312). No differences were observed between the pre- and post-intervention group regarding gender, disease distribution, or pediatric early warning scores. The implementation showed favorable outcomes in the dimensions Effectiveness, Adoption, and Implementation. Healthcare professionals engagement was 95%, with 86% (19/22) of the implementation strategies successfully completed. Healthcare professionals' knowledge in the pre-intervention group (n = 109) improved from median 40 (IQR 28;52) to median 76 (IQR 64;84) in the post-intervention group (n = 104; p < 0.001). Clinically, the new guideline reduced adverse events (12 vs 4; p = 0.047), reduced the median minutes of bedside handover time from 5 (IQR 3;7) to 4 (IQR 3;5; p < 0.001), and improved handover information completeness from median score of 5 (IQR 4;6) to 20 (IQR 12;23, p < 0.001). The total transport time increased from 14 to 19 minutes in the post-intervention group (p < 0.05), while no significant changes were observed in handover interruptions or post-transfer vital sign stability (p > 0.05).
Conclusion:
The RE-AIM-based evaluation confirmed that the implementation strategies effectively enhanced healthcare professionals' knowledge and compliance while reducing adverse events and optimizing handover efficiency. However, the limited patient participation rate and increased transport duration highlight areas requiring further refinement to maximize the guideline's impact.
Trial Registration:
ClinicalTrials.gov, NCT06512805. Registered 27 June 2024.
