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Updated: Jun 9, 2026
Manufacturing Chimeric Antigen Receptor (CAR) T Cells for Adoptive Immunotherapy
Published on: December 17, 2019
Chimeric antigen receptor T-cell therapy induces complete remission in a patient with concurrent CLL with CNS
Dermot J Murphy1, Siba El Hussein1, Angela Applebee2
1University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT, USA.
Abstract:
In a patient with chronic lymphocytic leukemia (CLL) involving the central nervous system, and concurrent multiple sclerosis (MS), CD19-directed CAR T-cell therapy led to complete remission of CLL and marked improvement in MS disease burden.
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