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Updated: Jun 9, 2026

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
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Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

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Phosphodiesterase 8 (PDE8), a novel target for neurodegenerative diseases

Xuan Zhao1, Yi-Ting Fu1, Nian-Zhuang Qiu2

  • 1Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China.

Cellular Signalling
|June 7, 2026
PubMed

Keywords:
Alzheimer's diseaseCyclic adenosine monophosphate (cAMP)InflammationNeurodegenerative diseasesPhosphodiesterase 8 (PDE8)

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