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Related Experiment Videos

Motion sickness--key to neurobiologic variation.

C S Mirabile, B C Glueck

    The Journal of Clinical Psychiatry
    |April 1, 1979
    PubMed
    Summary

    Motion sickness susceptibility is linked to personality traits and psychiatric conditions. Specific medications like lithium and antidepressants show varied responses in individuals prone to motion sickness.

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    A clinically useful polling technique for assessing susceptibility to motion sickness.

    Perceptual and motor skills·1982

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Individual Differences

    Background:

    • Motion sickness susceptibility varies significantly among individuals.
    • This variation may reflect fundamental differences in orientation mechanisms.
    • Previous research suggests links to perceptual, cognitive, and personality factors.

    Purpose of the Study:

    • To investigate the association between motion sickness susceptibility and psychological variables in psychiatric patients.
    • To explore potential correlations with specific Minnesota Multiphasic Personality Inventory (MMPI) scales.
    • To examine drug responses in motion sickness-susceptible individuals.

    Main Methods:

    • Analysis of data from a clinical study of over 1,500 psychiatric inpatients.
    • Correlation of motion sickness susceptibility with MMPI scales (e.g., Social Isolation, Ego Strength, Schizophrenia).
    • Comparison of discharge conditions for patients on lithium, antidepressants, and other drug therapies.

    Main Results:

    • A clear association was found between motion sickness susceptibility and several MMPI scales.
    • Patients treated with lithium and antidepressants showed distinct differences in their condition at discharge compared to other drug groups.
    • These findings suggest specific drug responses within the motion sickness-susceptible population.

    Conclusions:

    • Motion sickness susceptibility is a relevant individual difference marker in psychiatric populations.
    • Psychological and personality factors, as measured by MMPI, are significantly associated with motion sickness.
    • Pharmacological interventions may need to consider individual motion sickness susceptibility due to differential drug responses.

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