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Impact of an Intradialytic Nonimmersive Virtual Reality Platform on Functional Capacity: The GoodRENal Pilot
Eva Segura-Orti1, Evangelia Kouidi2, Vasiliki Michou2
1Department of Physiotherapy, Universidad Cardenal Herrera-CEU, CEU-Universities, Valencia, Spain.
Kidney Medicine
|June 8, 2026
Summary
Sedentary hemodialysis patients can improve muscle strength with the GoodRENal virtual reality (VR) platform. This feasible and safe intradialytic exercise intervention increased lower-limb strength and maintained gait speed.
Area of Science:
- Nephrology
- Gerontology
- Rehabilitation Medicine
Background:
- Sedentarism and low health-related quality of life (HRQoL) are prevalent in hemodialysis patients.
- Innovative interventions are needed to improve HRQoL and physical function in this population.
Purpose of the Study:
- To investigate the feasibility and safety of the GoodRENal virtual reality (VR) platform for intradialytic exercise.
- To assess the impact of this intervention on physical function and muscle strength in hemodialysis patients.
Main Methods:
- A 4-to 12-week randomized controlled trial comparing the GoodRENal intervention group (GIG) with a usual care control group (CG).
- The GoodRENal platform delivered VR scenarios for physical activity, nutrition, psychological well-being, and cognitive function.
- Primary feasibility outcomes included recruitment, retention, and adherence rates; physical performance and muscle strength were secondary outcomes.
Main Results:
- Recruitment rate was 53.2%, with high retention (91-100%) and adherence (61-100%). No adverse effects were reported.
- The GIG showed a significant increase in lower-limb muscle strength (hip flexors and abductors) after 12 weeks.
- Gait speed decreased in the CG but was preserved in the GIG.
Conclusions:
- The GoodRENal VR platform is a feasible and safe intradialytic exercise intervention.
- The intervention effectively increased lower-limb muscle strength in hemodialysis patients.
- Further research with larger samples is recommended to confirm effectiveness over longer periods.
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