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Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
11:13

Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

Published on: April 7, 2016

TGIF1-mediated corneal fibrosis inhibition: a gene-editing alternative to keratoplasty?

Erum Habib1, Ushna Saad2, Numan Aslam2

  • 1Department of Ophthalmology and Visual Sciences, Dow University of Health Sciences, Karachi Pakistan.

Annals of Medicine and Surgery (2012)
|June 8, 2026
PubMed
Abstract

No abstract available in PubMed .

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...

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