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Updated: Jun 9, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
Propyl 4-amino-benzoate
Alexander J Gutzwiller1, Christine K F Hermann1, George N Harakas1
1PO Box 6949, Radford University, Radford, Virginia 24142, USA.
Abstract:
The structure of the title compound, C10H13NO2, shows the n-propyl group to be perpendicular to the remaining part of the mol-ecule; carboxyl-ate-C-O-C-C(n-prop-yl) torsion angle = -87.05 (19)°. In the crystal, amine-N-H⋯O(carbon-yl) and weaker amine-N-H⋯N(amine) hydrogen bonding occurs within double layers parallel to the ab plane. The hydrogen atoms of the methyl group are disordered over two sets of sites in the ratio 0.89 (3) to 0.11 (3).
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