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Related Concept Videos

Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Updated: Jun 9, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Dermatoscopic Features of Hyperpigmented Dermatoses.

You Hua1, Bo Xie1, Yuqing Shen1

  • 1Department of Dermatology, Hangzhou Third People's Hospital, Hangzhou, People's Republic of China.

Clinical, Cosmetic and Investigational Dermatology
|June 8, 2026
PubMed
Summary
This summary is machine-generated.

Dermatoscopy is a valuable tool for diagnosing non-melanocytic hyperpigmented skin conditions. This review details key dermatoscopic features for accurate diagnosis and differential diagnosis of these common disorders.

Keywords:
dermatoscopyhyperpigmented dermatosesmelasma

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Area of Science:

  • Dermatology
  • Medical Diagnostics

Background:

  • Dermatoscopy, initially for melanocytic lesions, is now vital for non-melanocytic hyperpigmented disorders.
  • These conditions present diagnostic challenges and significant patient distress.

Purpose of the Study:

  • To provide a practical overview of dermatoscopic findings in common non-melanocytic hyperpigmented conditions.
  • To highlight dermatoscopy's role in enhancing diagnostic accuracy.

Main Methods:

  • Review of current literature on dermatoscopic manifestations.
  • Compilation of characteristic dermatoscopic features for various hyperpigmented dermatoses.

Main Results:

  • Melasma, nevus of Ota, lentigines, seborrheic keratosis, and others show distinct dermatoscopic patterns.
  • Characteristic features aid in differentiating these conditions.

Conclusions:

  • Dermatoscopy is an essential, non-invasive method for evaluating non-melanocytic hyperpigmented skin conditions.
  • It improves diagnostic accuracy and aids in differential diagnosis, benefiting patient care.