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Education and regular Feedback for Antimicrobial Stewardship in nursing homes: EduFAST study protocol
Irene Sotillo-Sánchez1,2, Laura Herrera-Hidalgo1,2,3,4, Cintia Flores-Rubio5
1Department of Pharmacy, Virgen del Rocio University Hospital, Seville, Spain.
Frontiers in Medicine
|June 8, 2026
Summary
This study introduces EduFAST, a web platform to improve antimicrobial stewardship in nursing homes. It aims to reduce antimicrobial use and resistance, benefiting both patient health and the environment.
Area of Science:
- Gerontology
- Infectious Diseases
- Environmental Science
Background:
- Nursing homes face challenges with antimicrobial use due to an aging population, polypharmacy, and comorbidities.
- Antimicrobial Stewardship Programs (ASPs) are crucial for reducing antimicrobial consumption and improving prescribing practices in these settings.
- Limited implementation of ASPs in nursing homes necessitates innovative solutions.
Purpose of the Study:
- To develop and evaluate the EduFAST web platform for training professionals and monitoring antimicrobial use and resistance in nursing homes.
- To assess the impact of the EduFAST platform on antimicrobial consumption, resistance patterns, and environmental markers.
- To facilitate the implementation and sustainability of ASPs nationwide.
Main Methods:
- A 12-month quasi-experimental, multicenter, before-and-after study implementing ASP strategies via the EduFAST web platform.
- Data collection included web platform usage, user satisfaction, knowledge gained, clinical variables, antimicrobial consumption, and resistance data.
- Wastewater analysis was conducted to correlate antimicrobial presence, resistance genes, and consumption, adopting a One Health perspective.
Main Results:
- The study is designed to evaluate the impact of the EduFAST platform on key antimicrobial stewardship metrics.
- Analysis will include interrupted time series, trend analysis, and regression models to assess intervention effectiveness.
- Wastewater data will be analyzed for correlations between clinical and environmental antimicrobial resistance markers.
Conclusions:
- The EduFAST platform aims to enhance the implementation and sustainability of antimicrobial stewardship programs in nursing homes.
- Wastewater analysis provides novel insights into the environmental impact of antimicrobial use and resistance.
- This initiative supports a One Health approach by linking human health, animal health, and environmental quality.
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