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Published on: January 28, 2014
Cardiovascular Disease Risk Estimation Using Blood Biomarkers and the QRISK3 Stratification Tool: A Cross-Sectional
Ahmed Salem1, Fanar Alsmarat1, Tasneem Al-Awaideh2
1Department of Anatomy, Physiology and Biochemistry, Faculty of Medicine The Hashemite University Zarqa Jordan.
Health Science Reports
|June 8, 2026
Summary
A significant portion of Jordanians face elevated cardiovascular disease (CVD) risk, with smoking increasing this likelihood. Early screening and intervention are crucial for managing CVD risk in the population.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular diseases (CVD) represent the primary cause of mortality in Jordan.
- Assessing 10-year CVD risk and associated biomarkers is vital for public health initiatives.
Purpose of the Study:
- To estimate the prevalence of 10-year CVD risk using the QRISK3 tool in a Jordanian sample.
- To evaluate fibrinogen levels and lipid profiles as supplementary CVD risk indicators.
Main Methods:
- A cross-sectional study was conducted in Amman, Jordan, involving 251 participants aged 25-64.
- Data collection included questionnaires and blood sample analysis for fibrinogen and lipid profiles.
- The study adhered to STROBE guidelines for observational research.
Main Results:
- 31.1% of participants had a QRISK3 score ≥10%, and 14.3% had a score >20%.
- Active smokers exhibited higher CVD risk scores and prevalence of atrial fibrillation.
- 77.7% had non-optimal lipid profiles, with longer-term smokers showing lower HDL levels.
Conclusions:
- A substantial proportion of the study sample faces elevated CVD risk, particularly smokers.
- Findings highlight the need for routine CVD risk screening in primary care for early intervention.
- Limitations include convenience sampling and small sample size, restricting generalizability to the entire Jordanian population.
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