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Updated: Jun 9, 2026
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Combined chemotherapy with sequential allogeneic hematopoietic stem cell transplantation successfully treats primary
Xiushuai Dong1, Jinghua Wang1, Yaoyao Tian1
1Department of Hematology, The Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Abstract:
Primary plasma cell leukemia (pPCL) is an extremely aggressive and rare subtype of plasma cell neoplasm with extremely poor prognosis, and optimal treatment strategies remain controversial due to its low incidence. This case is unique in that it reports long-term disease-free survival after combination chemotherapy followed by allogeneic peripheral blood hematopoietic stem cell transplantation (allo-PBSCT), which provides valuable real-world evidence supporting the potential curative role of this sequential therapeutic approach for pPCL, a disease where long-term survival is rarely achieved with conventional treatments.
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