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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

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Related Experiment Video

Updated: Jun 9, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
05:00

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction

Published on: April 1, 2019

Deep Cleaning Device as a Treatment Is Effective for Blepharitis and Significantly Reduces Bacterial Load.

Ya Wen1,2,3,4, Jiayu Bao1,2,3,4, Ao Li1,2,3,4

  • 1Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China, ccmu.edu.cn.

Journal of Ophthalmology
|June 8, 2026
PubMed
Summary

The Deep Cleaning Device effectively treats blepharitis by reducing bacterial load and improving symptoms. This device offers a safe and valuable addition to conventional blepharitis therapies.

Keywords:
bacterial loadblepharitisdeep cleaning deviceocular surface healthtreatment

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Last Updated: Jun 9, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
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Published on: April 1, 2019

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07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

Area of Science:

  • Ophthalmology
  • Medical Devices
  • Microbiology

Background:

  • Blepharitis is a common inflammatory condition affecting the eyelid margins.
  • Current treatments for blepharitis often involve lid hygiene and topical medications.
  • There is a need for innovative and effective therapeutic options for blepharitis management.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Deep Cleaning Device for blepharitis treatment.
  • To compare a combined therapy (device + eye drops) with monotherapy (eye drops alone).

Main Methods:

  • A prospective, randomized controlled trial with 51 adult patients diagnosed with blepharitis.
  • Group A received sodium hyaluronate eye drops plus weekly device-assisted eyelid margin cleaning.
  • Group B received sodium hyaluronate eye drops as monotherapy. Efficacy and safety outcomes were assessed.

Main Results:

  • The device group showed significant reductions in bacterial load and subjective symptoms compared to the control group.
  • Objective measures, including eyelid margin scale and meibum quality, improved significantly with the device.
  • No significant adverse effects on visual acuity or intraocular pressure were observed.

Conclusions:

  • The Deep Cleaning Device is a safe and effective treatment for blepharitis.
  • It significantly reduces bacterial load and alleviates clinical symptoms.
  • The device is a valuable adjunct to existing blepharitis therapies.