Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Rheumatic Heart Disease IV: Nursing Management

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The application of probe-based confocal laser endomicroscopy in pleural diseases.

Medicine·2026

Same author

Diagnostic yield and safety of needle-based COnfocaL LAser endomicroscopy and ultrasound-guided pleural BiOpsy in diagnosing patients with unknown pleuRAl effusion: a protocol for a mulTIcenter, randomized cONtrolled trial (COLLABORATION-II).

Respiratory research·2026

Same author

Diagnosis of malignant pleural effusion using thoracoscopy combined with confocal endomicroscopy: a case report.

American journal of translational research·2026

Same author

Clinical application of confocal laser endomicroscopy in the diagnosis of malignant pleural effusion.

Frontiers in oncology·2026

Same author

Bronchial myeloid sarcoma secondary to acute monoblastic leukemia (AML-M5): a rare Case Report.

Frontiers in medicine·2025

Same author

Integrating ryegrass-maize intercropping systems for mitigating Cd-Pb contamination: enhancing ecosystem services and habitat sustainability.

Scientific reports·2025

Search research articles

Related Experiment Video

Updated: Jun 9, 2026

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Published on: May 19, 2023

Pulmonary Rheumatoid Nodules: A Case Report.

Mingli Yuan¹, Wen Yin¹, Liangchao Wang¹

¹Department of Pulmonary and Critical Care Medicine Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.

Respirology Case Reports

|June 8, 2026

Summary

Pulmonary rheumatoid nodules (PRNs) are rare lung manifestations of rheumatoid arthritis (RA). This case highlights diagnostic methods for PRNs, distinguishing them from other lung conditions.

Keywords:

case report pulmonary nodules rheumatoid arthritis rheumatoid nodules

Related Experiment Videos

Last Updated: Jun 9, 2026

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Published on: May 19, 2023

Area of Science:

Rheumatology
Pulmonology
Pathology

Background:

Rheumatoid arthritis (RA) is a systemic autoimmune disease.
The lungs are frequently affected in RA, manifesting as interstitial lung disease or pulmonary nodules.
Pulmonary rheumatoid nodules (PRNs) are uncommon but significant extra-articular manifestations.

Purpose of the Study:

To report a case of pulmonary rheumatoid nodules (PRNs) in a patient with rheumatoid arthritis.
To discuss the diagnostic challenges and methods for PRNs.
To emphasize the importance of differentiating PRNs from other pulmonary pathologies.

Main Methods:

Case presentation of a 74-year-old male with RA.
Computed tomography (CT) scans revealing multiple bilateral pulmonary nodules.
CT-guided percutaneous core needle biopsy for pathological examination.
Multidisciplinary consultation for diagnosis.

Main Results:

Pathology revealed lymphocytic and neutrophilic infiltration, eosinophilic necrosis, and multinucleated giant cells, without vasculitis.
Diagnosis of PRNs was confirmed after excluding other causes.
Tocilizumab was recommended for treatment.

Conclusions:

PRNs are a rare extra-articular manifestation of RA requiring careful diagnosis.
High-resolution chest CT and biopsy are crucial for accurate diagnosis.
Distinguishing PRNs from infections and malignancies is essential for appropriate management.