Related Experiment Video
Updated: Jun 9, 2026
10:04
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Female Genital Tuberculosis, Ghana: A Case Report
Anthony K Dah1, Dennis Brempong2, Paschal K Dah3
1Department of Obstetrics and Gynaecology, School of Medicine University of Health and Allied Sciences Ho Ghana.
Clinical Case Reports
|June 8, 2026
Summary
Female genital tuberculosis often causes infertility and amenorrhea, especially in endemic areas. Diagnosis requires hysteroscopy and histopathology, even if molecular tests are negative, for effective management.
Area of Science:
- Reproductive Medicine
- Infectious Diseases
- Gynecology
Background:
- Female genital tuberculosis (FGTB) is a significant, often overlooked, contributor to infertility and amenorrhea.
- Prevalence is highest in tuberculosis-endemic regions, impacting reproductive health outcomes.
- Current diagnostic methods may not always be sufficient, leading to underdiagnosis.
Purpose of the Study:
- To highlight the diagnostic challenges of female genital tuberculosis.
- To emphasize the utility of hysteroscopy and histopathology in confirming FGTB.
- To advocate for a high index of suspicion and multimodal diagnostic approaches for unexplained infertility.
Main Methods:
- Review of diagnostic techniques for female genital tuberculosis.
- Emphasis on hysteroscopy and histopathology as key confirmatory methods.
- Discussion of limitations of molecular testing in certain FGTB cases.
Main Results:
- Hysteroscopy combined with histopathology provides definitive diagnosis of FGTB.
- This multimodal approach can confirm FGTB even when molecular diagnostic tests yield negative results.
- Unexplained infertility in endemic areas warrants thorough investigation for FGTB.
Conclusions:
- Female genital tuberculosis is a critical cause of infertility and amenorrhea that requires increased clinical awareness.
- Integrated diagnostic strategies, including hysteroscopy and histopathology, are essential for accurate FGTB diagnosis.
- Prompt and accurate diagnosis is crucial for managing infertility in women with suspected FGTB.
Related Concept Videos
01:28Pulmonary Tuberculosis V
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
01:26Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:23Tuberculosis
Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...