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Maxillofacial Cemento-Ossifying Fibroma: A Rare Case Report
Alix N Kamina1, Elisée Ntambua Mbombo1,2, Patrick Badibanga3
1Public Health Department Université Officielle de Mbujimayi Mbuji-Mayi Democratic Republic of the Congo.
Clinical Case Reports
|June 8, 2026
Summary
Cemento-ossifying fibroma is a rare jaw lesion. Accurate diagnosis requires correlating clinical, radiographic, and histopathological findings for effective treatment.
Area of Science:
- Oral and Maxillofacial Surgery
- Pathology
- Radiology
Background:
- Cemento-ossifying fibroma (COF) is an uncommon benign jaw neoplasm.
- Clinical presentation, often swelling, can mimic other osteo-fibrous lesions, complicating diagnosis.
- Radiological and histological findings may also be misleading.
Purpose of the Study:
- To report a rare case of COF in the maxillary region.
- To highlight diagnostic challenges and emphasize the importance of integrated diagnostic methods.
Main Methods:
- Case presentation of a 22-year-old female with a 10-year history of a maxillary mass.
- Diagnostic workup included clinical examination, computed tomography (CT) scan, and histopathological analysis.
- Surgical enucleation and curettage were performed.
Main Results:
- The tumor presented as a bulky, ulcerated mass in the upper right maxillary region.
- CT scan revealed a well-circumscribed mass with mixed density and calcified foci.
- Histopathology showed fibrocollagenous tissue within a cellular stroma, leading to a final COF diagnosis after initial suspicion of osteoblastoma.
Conclusions:
- The lateral maxillary location of this COF case is unusual.
- A definitive diagnosis of COF necessitates the correlation of histopathological findings with clinical and radiological data.
- Integrated diagnostic approaches are crucial for accurate COF diagnosis and management.
