Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal Wet Gangrene With Early Auto-Amputation in a Resource-Limited Setting With Incomplete Etiologic Workup: A

Milki Tufa Feyisa1, Beza Eshetu2, Tolosa Dibisa3

  • 1Jimma University Jimma Ethiopia.

Clinical Case Reports
|June 8, 2026
PubMed
Summary

Related Concept Videos

Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conservative Management Enabling Spontaneous Passage of an Idiopathic Primary Spontaneous Enterolith: A Case Report and Literature Review.

Clinical case reports·2026
Same author

Tracheal Extramedullary Plasmacytoma Causing Near-Complete Airway Obstruction in an HIV-Positive Man: A Case Report and Brief Literature Review.

Clinical case reports·2026
Same author

Recurrent Symptomatic Hyponatremia Revealing a Late Diagnosis of Sheehan Syndrome and Effectively Treated With Levothyroxine: A Case Report and Brief Review of Literature.

Clinical case reports·2026
Same author

Miliary Tuberculosis With Immune Thrombocytopenia in 50-Year-Old Ethiopian Woman: A Case Report and Brief Review of Literature.

Clinical case reports·2026
Same author

Health-related quality of life and associated factors among adult tuberculosis patients in Kembata Zone, Southern Ethiopia: a mixed-methods cross-sectional study.

BMC infectious diseases·2026
Same author

Guillain-Barré Syndrome Following Malaria: A Rare Case Report From Rural Ethiopia and Literature Review.

Clinical case reports·2025

Neonatal limb gangrene with auto-amputation is a rare condition requiring prompt medical attention. Early diagnosis and treatment, including antibiotics and surgery, are crucial for preserving growth and enabling future prosthesis use.

Area of Science:

  • Neonatology
  • Pediatric Surgery
  • Vascular Medicine

Background:

  • Neonatal limb gangrene with auto-amputation is a rare and often idiopathic condition.
  • Early recognition and intervention are critical for optimal outcomes in affected neonates.
  • Resource limitations can pose challenges to thorough etiologic workup.

Purpose of the Study:

  • To emphasize the importance of early recognition and management of neonatal limb gangrene.
  • To outline critical steps in the etiologic workup and treatment of this rare condition.
  • To highlight the necessity of preserving growth plates during surgical intervention.

Main Methods:

  • Review of clinical presentation and management strategies for neonatal limb gangrene.
  • Emphasis on prompt referral and comprehensive diagnostic evaluation.
Keywords:
Ethiopiaauto‐amputationneonatal gangrenenewbornwet gangrene

Related Experiment Videos

  • Discussion of therapeutic interventions including antibiotics, wound care, and surgical amputation.

    • Main Results:

    • Timely intervention is associated with better outcomes in neonatal limb gangrene.
    • Surgical amputation, when necessary, should aim to preserve growth plates.
    • Appropriate management can facilitate future prosthesis fitting.

    Conclusions:

    • Neonatal limb gangrene necessitates urgent recognition, referral, and workup.
    • Wet gangrene requires immediate broad-spectrum antibiotics and wound care.
    • Surgical amputation is vital for limb salvage and functional recovery, preserving growth potential.