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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Pericarditis II: Clinical Features and Diagnostic Tests01:19

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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

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Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Updated: Jun 9, 2026

Posterior Approach for Debridement of the Psoas Abscess
06:02

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Published on: March 2, 2020

CPPD-Induced Iliopsoas Bursitis Mimicking Pyomyositis.

Hiroki Okunobu1, Shinnosuke Fukushima1,2,3, Hideharu Hagiya3

  • 1Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.

Clinical Case Reports
|June 8, 2026
PubMed
Summary
This summary is machine-generated.

Calcium pyrophosphate deposition disease can resemble an iliopsoas abscess. Combining polarized light microscopy and 16S rRNA gene analysis helps differentiate crystal inflammation from infection, avoiding unnecessary antibiotics.

Keywords:
16S rRNAabscesscalcium pyrophosphate deposition diseaseculture‐negativedirect sequencing analysis

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Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Calcium pyrophosphate deposition disease (CPPD) is a crystal-induced arthropathy.
  • CPPD can present with symptoms that mimic infectious processes, such as an iliopsoas abscess.
  • Accurate differentiation is crucial for appropriate patient management.

Purpose of the Study:

  • To evaluate diagnostic methods for distinguishing CPPD from iliopsoas abscess.
  • To assess the utility of polarized light microscopy and 16S rRNA gene analysis in this context.

Main Methods:

  • Review of imaging findings in CPPD mimicking iliopsoas abscess.
  • Analysis of diagnostic performance of polarized light microscopy for crystal identification.
  • Application of 16S rRNA gene sequencing for bacterial detection in relevant samples.

Main Results:

  • Imaging findings of CPPD can be indistinguishable from iliopsoas abscess.
  • Polarized light microscopy reliably identifies calcium pyrophosphate crystals.
  • 16S rRNA gene analysis effectively detects bacterial pathogens.

Conclusions:

  • Combined use of polarized light microscopy and 16S rRNA gene analysis provides accurate differentiation between CPPD and infectious iliopsoas abscess.
  • This approach can prevent unnecessary antimicrobial therapy in cases of CPPD.