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Updated: Jun 9, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Hot-clot Artifacts in the Lung Parenchyma on 18F-CXCR4 PET/CT
Ying Kan1, Siqi Li1, Bingyan Zhang1
1Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Xi Cheng District, Beijing, China.
Abstract:
A 65-year-old woman underwent 18F-CXCR4 PET/CT for evaluation of a left adrenal lesion, which demonstrated marked radiotracer uptake, suggestive of an aldosterone-producing adenoma. Incidentally, intense focal uptake was observed in the anterior segment of the right upper lobe on PET imaging; however, no corresponding abnormality was identified on co-registered CT. This finding represents a pulmonary hot-clot artifact, a phenomenon previously documented with other radiotracers, including 18F-FDG, 99mTc-MDP, 99mTc-MIBI, 68Ga-DOTANOC, 68Ga-PSMA, and 177Lu-DOTATATE.
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