Related Experiment Video For 18F-FDG PET/CT
Updated: Jun 9, 2026
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
More Impressive 18 F-FDG PET/CT Findings Than 68 Ga-DOTA-FAPI-04 in a Cervical Chordoma
Tingting Xu1,2,3,4, Ke Cheng1,2,3,4, Ya Liu1,2,3,4
1Department of Nuclear Medicine, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Abstract:
Chordoma is a rare malignant bone tumor derived from notochordal remnants, typically occurring in the axial skeleton. Herein, we report a case of an 81-year-old woman with a cervical chordoma involving the C1-C5 vertebrae. The lesion demonstrated intense 18 F-FDG uptake but minimal 68 Ga-DOTA-FAPI-04 accumulation. This discordant imaging pattern highlights that while FAPI-targeted PET/CT is a promising pan-cancer imaging modality, its uptake in chordoma may be heterogeneous, potentially influenced by the tumor microenvironment or specific histologic subtypes.
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