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Updated: Jun 9, 2026
07:41
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
Nanomaterials in Melanoma Immunotherapy: A 20-Year Bibliometric and Visualization Analysis
Lei Zhao1, Jingyu Jin2, Yinli Luo1
1Department of Dermatology, Yanbian University Hospital.
The Journal of Craniofacial Surgery
|June 8, 2026
Summary
Nanomaterials show promise for enhancing melanoma immunotherapy by addressing low response rates and resistance. Research trends reveal increasing publications, with China and the US leading, focusing on anticancer mechanisms and nanoplatforms.
Area of Science:
- Oncology
- Materials Science
- Immunotherapy
Background:
- Melanoma is an aggressive cancer.
- Current immunotherapy has limitations like low response rates and acquired resistance.
- Nanomaterials offer potential to improve melanoma immunotherapy.
Purpose of the Study:
- To conduct a bibliometric analysis of research on nanomaterials for melanoma immunotherapy.
- To identify research status, trends, major contributors, and emerging hotspots in this field.
Main Methods:
- Bibliometric analysis of 935 publications from 2006-2025.
- Data sourced from Web of Science Core Collection (Science Citation Index Expanded).
- Analysis tools included VOSviewer, CiteSpace, Bibliometrix R package, and Excel.
Main Results:
- A steady increase in publications from 2006-2025.
- China and the United States are leading contributors in publications and institutions.
- Key journals include ACS Nano, Journal of Controlled Release, and Biomaterials.
- Top research hotspots: anticancer mechanisms, multifunctional nanoplatforms, and combinatorial therapeutic strategies.
Conclusions:
- Research in nanomaterial-enhanced melanoma immunotherapy is rapidly growing.
- Future research should focus on precision immunotherapy and clinical translation of nanomedicine approaches.
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