Related Experiment Video
Updated: Jun 9, 2026

Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks
Published on: June 9, 2023
Electrochemical Investigation of Cu(II) Complexation with a Novel Pyridine-Based Schiff Base Ligand: Cyclic
Elsayed M AbouElleef1, Rania A H Saad2, M A Diab2
1Basic Sciences Department, Delta Higher Institute for Engineering & Technology, 35681-Dakhlia, Mansoura, Egypt. s.abouelleef@yahoo.com.
Abstract:
This study investigates the electrochemical interaction between CuCl2 and a pyridine-based Schiff base ligand in aqueous KCl using cyclic voltammetry at 302.15 K. Significant shifts in peak potentials and currents confirmed stable Cu(II)-ligand complex formation. Kinetic and thermodynamic parameters revealed diffusion-controlled processes and favorable complexation with negative Gibbs free energy values. Molecular docking studies were conducted on the free ligand against the SARS-CoV-2 protein (7JWY), showing moderate binding affinity through hydrogen bonding interactions. The ligand also exhibited antioxidant activity with an IC50 value of 0.154 mg mL- 1.
More Related Videos
11:38Quantifying the Binding Interactions Between Cu(II) and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
Related Concept Videos
Voltammetric Techniques: Cyclic Voltammetry
Extraction: Advanced Methods
Colors and Magnetism
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human eye.
Complexometric Titration: Ligands
Crystal Field Theory - Octahedral Complexes
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
EDTA: Chemistry and Properties