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Interpreting prophylactic antibiotic use in closed basilar skull fractures: caution in claims-based evidence

Yancheng Wang1

  • 1Department of Nursing, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences Shanghai, China.

The Journal of Trauma and Acute Care Surgery
|June 8, 2026
PubMed
Abstract

No abstract available in PubMed .

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Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...

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